...Anacin (aspirin + caffeine) and banana each day gave a man, Sanchez-Blazquez of Grand Island, N.Y.,112 years of life. Probably, banana prevented gastric erosion by aspirin and aspirin itself helped repairing of normal wear and tear of tissues.

P.S. HearIng might be affected because NSAIDs inhibit vasodialating prostacyclin.

Aspirin is not a NSAID, rather it would thin the blood by inhibiting thromboxane in low doses and improve blood flow.

Preemptive analgesia (taking analgesia before injury) does help to prevent the ongoing tissue damage process and thus pain occurrence is slowed or prevented.

Paracetamol is also not a NSAID, acts centrally, depletes glutathione in the liver and has mostly antipyretic and little analgesic effect.

Continuous long term use should be avoided; plenty of water to wash out is necessary. No risk, no gain but need to take calculated risk with precaution.

World's Oldest Man Says He Owes Longevity to Anacin Tablets, Bananas:
http://abcnews.go.com/US/worlds-oldest-man-owes-longevity-anacin-tablets-bananas/story?id=19779550

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