EXPLAINING SIMPLY

....HOW to calculate BE (base excess or deficit)? ....it requires to know pH, which stands for "potential of hydrogen ion" and is defined as the negative logarithm to the base 10 of hydrogen ion concentration. ....normal pH is 7.35 - 7.45 and the normal hydrogen ion concentration is 40 nmol/L. ....Base excess/deficit of +/- 2 mEq/L is normal. A positive number is called a base excess and indicates a metabolic alkalosis and a negative number is called a base deficit and indicates a metabolic acidosis. Base Excess / Base Deficit --------------------------- Calculation of the base excess or deficit is a way of quantifying HCO3 requirement! ...."Base excess is the quantity of base (HCO3 mEq/L) that is above or below the normal range of buffer base in the body (22 -28 mEq/L). This cannot be calculated from PCO2 and pH alone as the hemoglobin also contributes to the buffer base. One can use the Siggaard-Andersen nomogram to estimate base excess or deficit. Another...

...half life determines the duration of drug effect; half life = (Volume of distribution divided by clearance) x 0.693 Or half life = Time constant x 0.693 Or Time Constant = Volume of distribution divided by Clearance. 1 half life = 50% of the amount of drug remaining in  the body. 2 half life = 25% of the amount of drug remaining in  the body. 3 half life = 12.5% of the amount of drug remaining in  the body. 4 half life = 6.25% of the amount of drug remaining in  the body. 5 half life = 3.125% of the amount of drug remaining in  the body. Time constant is longer than the Half life. In one time constant decreases to 36.8% (up to less than 50% - that is to say - one time constant takes longer time than one half life) But, if the system is about increase rather than decrease - it increases to 63.2% in one time constant. The time constant represents the elapsed time required for the system response to decay to zero if the system had cont...

...'the quality or state of being conscious or aware of something.' P.S. Mindfulness requires repeating and recalling the details of the present environment - thus avoiding the distractions. Mindfulness: http://www.nhs.uk/conditions/stress-anxiety-depression/pages/mindfulness.aspx

..."The Elisha Gray and Alexander Graham Bell controversy concerns the question of whether Gray and Bell invented the telephone independently." P.S. In order to date the invention or discovery, the simplest way is to post to one's own address; it gets dated - if "war" about who first ensues later. Invention can be at "ideation", "theoretical" or "Practical" level but for patenting it should be a marketable product or at least associated with a marketable product. Salman Rushdie could get his otherwise non-marketable expression "Naughty But Nice" by associating it with advertisement of a cream chocolate. Einstein could not get his equation E=mc2 patented because it is a concept. But, he could get his blouse design patented because it is a marketable product. https://en.m.wikipedia.org/wiki/Elisha_Gray_and_Alexander_Bell_telephone_controversy

...choose to DO or THINK about before the ENERGY goes away. P.S. Use it or lose it! Reenergise: http://www.deadlinenews.co.uk/2017/03/08/freerunner-goes-viral-sensational-tribute-trainspottings-opening-scene/

...Spiritual Intelligence (SQ) develops with tolerance and forgiveness; Emotional Intelligence (EQ) develops with adapting to the changing environment and Mental Intelligence (IQ) develops with repetition and practice. P.S. - ability to tell that two plus two is 4 implies Mental Intelligence (IQ); adapting to accept that 2 + 2 can be 5 is Emotional Intelligence (EQ) (put 2 mice in a box and 2 more mice in the same box, upon opening after a month, there can be 5 mice, isn't it?) and Spiritual Intelligence implies 2 + 2 can be infinity - soul out of the body wandering in the Universe - relieved from the materialistic world - ready to tolerate and forgive because own existence can be equal to Zero without the body which will perish and the soul will be released to the infinite Universe. Autobiography of a yogi: https://www.ananda.org/free-inspiration/books/autobiography-of-a-yogi/

...better to match the seizure with enough oxygen - it is like a brain stimulant - can have great creative power. P.S. - better to harness the creative potential during the lucid period. Probably, epileptic patients be given "home oxygen" to avail during seizure attacks because during such excessive electrical discharge more oxygen is needed to prevent anaerobic metabolism and the resulting brain oedema causing brain cell death eventually. How to prevent seizures: http://www.everydayhealth.com/epilepsy/preventing-epilepsy-seizures.aspx

...there is usually very LITTLE TIME before the future becomes the present; so, better to begin NOW itself!

...never consider an idea laughable; just write down and "ruminate" and "incubate" the 'brainchild'. P.S. ...better to post to oneself through post office before disclosing to anyone; it gets dated - to be prepared if a "war" for patenting ensues - who first?

...discoveries and inventions are to make everyday life comfortable, not otherwise. P.S. "Jugaad (alternatively Juggaar) is a colloquial Hindi-Urdu word that can mean an innovative fix or a simple work-around, used for solutions that bend rules, or a resource that can be used as such, or a person who can solve a complicated issue." 'Juggad' and invention are two different things; former is applicable in war zones and where resources are scarce, latter is possible in peace and where 'forging' companies (e.g. Menlo Park-https://en.m.wikipedia.org/wiki/Thomas_Edison) - can produce a product overnight, just need to get an idea! 'Sneak and Peep' policy particularly since 9/11 has almost legalised "phishing" of Intellectual Property through 'Windows', 'Mac' and others - nothing is secret on one's desktop. Speech by Charlie Chaplin: http://www.zerohedge.com/news/2016-05-08/greatest-speech-ever-more-relevant-ever

...better to consume all 20 odd amino acids and the digestive enzymes. P.S. - Carbohydrate and fat are generally taken in plenty; protein in its broken form of amino acids can build the breaking tissues and repair and heal. Amino acids: http://www.aminoacid-studies.com/amino-acids/what-are-amino-acids.html

..."A vaccine used over 100 years ago for tuberculosis (BCG - bacillus Calmette-Guerin) has shown promise in reversing diabetes. This vaccine is now commonly used for treating bladder cancer and is considered to be safe." P.S. BCG helps produce TNF which destroys T cells - the Beta cell killer. Trial at Boston: http://www.faustmanlab.org/docs/clinicalt/BCG%20TRIALS%20FACT%20SHEET.pdf

...some patterns do exist in this chaotic cosmos same as the electrical discharge from the heart is chaotic but by "Fourier analysis" some patterns are seen as ECG waves. P.S. Similarly, this "little beautiful yellow flower" is a "Fourier analysis by God" to exist out from this chaotic cosmos putting the necessary materials together as a "little beautiful yellow flower". Its existence has come for a while, before it withers away, eyes get the treat! Does Chaos Rule the Cosmos? http://discovermagazine.com/1992/nov/doeschaosrulethe147/

...appendix does "serve to seed" the gut again of its normal bacterial flora after a wash out by severe diarrhoea and dysentery. Appendix retains protected some of the bacterial flora in the side stream space; lymphoid tissues further protect from other insults. P.S. Like a "little curd" (joran in Hindi)  containing Lactobacillus is needed for fermenting and turning warm milk into curd overnight. 7 Signs Your Gut Bacteria Are Out of Whack: http://blog.paleohacks.com/7-signs-your-gut-bacteria-are-out-of-whack/

...Anacin (aspirin + caffeine) and banana each day gave a man, Sanchez-Blazquez of Grand Island, N.Y.,112 years of life. Probably, banana prevented gastric erosion by aspirin and aspirin itself helped repairing of normal wear and tear of tissues. P.S. HearIng might be affected because NSAIDs inhibit vasodialating prostacyclin. Aspirin is not a NSAID, rather it would thin the blood by inhibiting thromboxane in low doses and improve blood flow. Preemptive analgesia (taking analgesia before injury) does help to prevent the ongoing tissue damage process and thus pain occurrence is slowed or prevented. Paracetamol is also not a NSAID, acts centrally, depletes glutathione in the liver and has mostly antipyretic and little analgesic effect. Continuous long term use should be avoided; plenty of water to wash out is necessary. No risk, no gain but need to take calculated risk with precaution. World's Oldest Man Says He Owes Longevity to Anacin Tablets, Bananas: http://abcnews....

...everyone has cancer; only difference is that most people die due to other causes before cancer would appear. Everyone dies, only difference is about early & late and slow & fast death. P.S. - "However, many men never know they have prostate cancer. Autopsy studies of Chinese, German, Israeli, Jamaican, Swedish, and Ugandan men who died of other causes have found prostate cancer in 30% of men in their fifties, and in 80% of men in their seventies." https://en.m.wikipedia.org/wiki/Prostate_cancer Dying with Dignity: http://www.finalexitnetwork.org/

...good to walk till sweaty; helps produce more stem cells in bone marrow. P.S. Given that it is harder to pump in blood into bones. Stem Cells: http://www.mayoclinic.org/tests-procedures/bone-marrow-transplant/in-depth/stem-cells/art-20048117?pg=2

...education is to train the mind to THINK better; indeed the brain which was earlier caller a “cooler” processes the accumulated data, information, knowledge, experience and wisdom to arrive at a conclusion but in an illiterate person though there might be patchy information or experience, generally “short circuits” into a defective conclusion and are often “short tempered” relying more on their instinct (Id) than the “Ego” or the “Super Ego” which comes with more learning and wisdom; many “fuzz factors” need to be taken into consideration before arriving at a decision – for an example, the famous equation, E = mc^2 is just a mnemonic devised for easy remembering of a complex reality; actually, the proper equation together with the “fuzz factors” is E^2 = (mc^2 )^2 + (pc)^2 (^ stands for the power) - a fact to be vehemently denied by someone having little knowledge and would argue that E = mc^2; as we progress in life with our learning we tend to THINK more together with more and mor...

...Human Capital (health & education), Social Capital (family & friends) and Financial Capital (money & property). P.S. Need to prioritise according to the current circumstances. Capital: https://en.m.wikipedia.org/wiki/Capital_(economics)

...courage + science = fantastic acrobatics! P.S. Carrying a remote control in the right hand to control the flow and speed of water jet of this flyboard. FLYBOARDING EXPERIENCES: https://www.buyagift.co.uk/adventure/flyboarding?Channel=PPC&cm_mmc=google-_-ADV+-+Flyboarding+-+Exact-_-Flyboarding-_-flyboarding%20uk&mkwid=sN0CV4jQX_dm&pcrid=151161369753&pkw=flyboarding%20uk&pmt=e&DD=Adrenaline&gclid=CjwKEAjw3drIBRCOwfC-_qqyjQ8SJADvoWQp-O_oEsW3GxO3BfnZSa9-vUwGgSFrQ9s64tiAm92eGhoCZ27w_wcB